CRM® - Dermal Fillers
This product was introduced to the UK in March of 2008. It is manufactured by a German company which is also known to have produced Matridur and Matridex. It has yet to gain much prominence in the UK market, and so not many practitioners are known to currently use this product. Overall it produces good results according to relevant feedback. It uses butanediol diglycidyl ether (BDDE), an agent for cross-linking, which is one of the most popular cross-linking agents that have increased resistance against gel degradation. This adds to the credibility of the product as gel degradation is a factor that many practitioners take into account. The resistance determines the durability and general quality levels, and it is also less toxic.
A non–animal hyaluronic acid gel, CRM is charged positively within two product formulations and is made by fermentation of streptococci bacteria. It is not permanent in constituency since hyaluronic acid eventually breaks down in the body, and another treatment will be necessary to recreate the desired aesthetics. The product comes in five kinds: crm-DEX™, crm-DX™, crm-GEL™, crm-DUR™ and crm-SOFT™.
In terms of crm-DEX™ it is 17mg/ml of hyaluronic acid and 25mg/ml of dextranomer. It can be used for treating deep wrinkles and folds such as nasolabial and marionette. It can also be used for lip augmentation. The recommended amount is one 1ml syringes applied with a needle of 27 gauges. Crm-DX™ is made up of 17mg/ml of acid and 50mg/ml of dextranomer.
It can be used for treatments involving facial or cheek contours, with amounts and syringe specification similar to crm-DEX™. Crm-GEL™ uses 4mg/ml of pure acid and 16mg/ml of cross-linked acid. It is designed for use in treating folds, lip augmentation and deep wrinkles with 29 gauge needles. Crm-DUR™, 14mg/ml of cross-linked hyaluronic acid, is suitable for wrinkles around the mouth and eyes, as well as superficial lines on the face.
The crm-SOFT™ product uses 14mg/ml of hyaluronic acid. It is suitable for bio rejuvenation and rehydration of the face, neck, hands and décolletage with the use of a mesotherapy technique. One 1ml syringes are appropriate with needles of gauge 30. Some of the expected side-effects include pain, swelling, itching and redness. Recovery is very quick, taking one to two days for skin injection and around one week for injections on the lips.