Matridur ® and Matridex ® - Dermal Fillers
A mixture of 25mg/ml stabilised, non-animal hyaluronic acid and 25mg/ml cross-linked hyaluronic acid, Matridur was introduced to the UK market in 2004. Matridex contains hyaluronic acid and dextranomer, which are essentially dextran molecules. This combination leads to the formation of microparticles that have a positively charged surface with an approximate diameter of 80-120 microns. These microns have found use in surgical operations where fast healing is needed, and they are also used in conditions where soft tissue needs to be recovered.
A good example for this kind of treatment is in treating incontinence. This involves regeneration, repairing and bulking of the urethra, which is a very delicate part of the body that requires gentle, effective handling. Skin tests before using the product are not required because most of the components are natural. They can be trusted not to have any advanced side-effects to the patient, though compatibility tests can be carried out if it is the patient's wish.
Due to the hyaluronic acid composition this product is a temporary treatment and repeat applications can be undertaken once the expected duration is over with. With time the acid is broken down completely and leaves no trace of the filler. It is at this time that another treatment may be required. It comes in two formulations: Matridur and Matridex. Matridex is normally used for smoker lines, perioral lines above the top lip and laughter lines that are commonly found around the eyes.
Individuals with hypersensitivity to hyaluronic acid, autoimmune disease, a tendency to develop hypertrophic scars, and breastfeeding and pregnant women must not use this product. The duration of Matridur depends on the degree of treatment required, lifestyle, age and the actual placement of the filler by a qualified practitioner. It normally lasts about 6 to 9 months on average. Depending on the part of the body to be treated the results of Matridex can last longer than Matridur, averaging roughly 12 to 24 months.
Some of the side-effects which can be expected include pain, swelling, itching, discolouration and tenderness at the implanted site. Recovery is normally very quick, taking about 1 to 2 days for skin injections and around one week for lips. Costs will depend on the area of treatment, practitioner and amount required. The range of cost per syringe is approximately £200 to £300.